There is no such thing as ‘spot-reducing.’ If you work your waist until sweat is pouring off your body, you will develop your abs and you will lose some fat. The fat loss, however, will come from all parts of your body, not just your abdominal area. Sure you can trim your waist by performing waist exercises, but your six-pack won’t show until you have rid your body of your subcutaneous adipose.
The best exercises you can perform to rid yourself of the fat over your abs is the exercise of self restraint and the exercise of good judgment. The restraint comes in when you are offered a choice between a piece of fruit or a piece of chocolate cake. Choose the fruit. The good judgment comes in when you set up a good fitness program and stick to it. More good judgment is exercised when you develop a good nutrition plan with lots of good protein, complex carbohydrates, good fats and fiber. Great judgment is shown when you stick to your plans and the body you really want begins to emerge from the lump that was on the couch.
All that being said (with a little tongue in cheek) good abs are not going to happen by themselves or from taking any supplements or little blue pills you buy in the locker room from Louie the Loop. They do require work in the form of exercise and a good bodybuilding diet.